Relationship between sperm chromatin status and ICSI outcome in men with obstructive azoospermia and unexplained infertile normozoospermia.

The evaluation of sperm chromatin status in men with different infertility factors, and its relationship with ICSI outcomes

One of the most important factors related to male fertility is sperm chromatin status. Under Assisted Reproductive Techniques (ART), especially Intracytoplasmic Sperm Injection (ICSI), the natural selection of high quality sperm with intact chromatin is not possible. Therefore, embryo quality and pregnancy rate decreased for damaged DNA of sperms involved in the fertilization of eggs. Thus, thi...

P-226: Association of ?-Defensin 126 Gene Alteration with Intra Cytoplasmic Sperm Injection and In Vitro Fertilization Outcome in Unexplained Infertile Men

Outcome of testicular sperm recovery and ICSI in patients with non-obstructive azoospermia with a history of orchidopexy.

BACKGROUND Little is known about sperm recovery and ICSI using testicular sperm from men with non-obstructive azoospermia who had a previous orchidopexy. We therefore studied the sperm recovery in this subgroup and evaluated clinical parameters predicting successful sperm retrieval and the outcome of ICSI. METHODS A total of 79 non-obstructive azoospermic men with a history of orchidopexy und...

Comparative study of intracytoplasmic sperm injection outcome from sperms retrieved by different procedures.

BACKGROUND Different sperm retrieval procedures can help retrieve sperms that can be used for Intracytoplasmic Sperm Injection (ICSI) in azoospermic men. The objective was to compare the Intracytoplasmic sperm injection outcome, through different sperm retrieval procedures in azoospermic men. METHODS A Retrospective Study was carried out at Islamabad Clinic Serving Infertile Couples from Sept...

Who should be screened for chromosomal abnormalities before ICSI treatment?

Guidelines on karyotyping infertile men before ICSI treatment are not consistent. Most guidelines recommend chromosomal screening in azoospermic and severe oligozoospermic men, because they are assumed to have the highest risk of abnormalities. We performed a retrospective cohort study in azoospermic men and men eligible for ICSI. We determined the prevalence of chromosomal abnormalities in rel...